Bachelor's degree in life sciences

– 2 ECTS

– 1.5 ECTS

– 3.5 ECTS

– 2 ECTS

– 2.5 ECTS

– 1.5 ECTS

– 4 ECTS – Faculty of Science

-3 ECTS – Faculty of Science

– 4 ECTS – Faculty of Science

– 4 ECTS – Faculty of Science

– 2 ECTS – Faculty of Science

– 2 ECTS

German/Spanish/Other – 2 ECTS

– 5 ECTS

– 5 ECTS

– 2.5 ECTS

– 4 ECTS

– 3.5 ECTS

– 2 ECTS

– 4 ECTS – Faculty of Science

– 5 ECTS – Objectives To train students in various techniques for analyzing both solutions and solids, enabling them to experimentally analyze and control active ingredients alone or in pharmaceutical forms, as well as pharmacokinetics.

• Know how to determine and characterize the crystal polymorphism of pharmaceutical substances using thermal and diffractometric methods.
• Analysis and measurement of various elements in pharmaceutical substances/blood/urine using atomic spectrophotometry.
• Conceptualization and modeling of Newtonian, non-Newtonian, and viscoelastic behaviors. Application to viscometric and rheological measurements of healthcare products.
• Introduction to analytical separation methods and their coupling with mass spectrometry for the identification and quantification of xenobiotics.

Content (CM-TD-TP) The various analysis methods are presented in lectures and illustrated with numerous examples relating to medicines. A few hours of tutorials are devoted to demonstrating the complementary nature of all these techniques. Numerous practical sessions (32 hours/student) directly linked to the lectures enable students to familiarize themselves with the different types of equipment and thus gain a better understanding of all these techniques, both in terms of fundamentals and technical aspects. Speakers Montpellier University

– 5 ECTS – Objectives Pharmacology: Through pharmacology courses, students must acquire solid knowledge of the families of drugs covered. The pharmacology course describes the mechanism(s) of action of each family of drugs, the resulting pharmacological properties and therapeutic indications, the main pharmacokinetic parameters, side effects, drug interactions, and the main contraindications. Pharmacokinetics: By the end of the course, students should be able to:

• To describe the different stages of the journey of an active chemical ingredient (absorption, distribution, metabolism, and excretion) contained in a pharmaceutical product after administration to humans.
• To describe the different mechanisms involved during these stages
• Define the various pharmacokinetic parameters: bioavailability, distribution volumes, clearances, half-lives, etc.
• Calculate these parameters using non-compartmental analysis or pharmacokinetic models.

Toxicology: By the end of the course, students should be able to:

• To describe the general principle of the metabolization stage of an AP contained in a pharmaceutical product after administration to humans.
• Describe the different modes of action of a toxic substance.
• Describe the toxicology of ethanol and paracetamol.
• Describe the main stages of clinical investigation (preclinical studies)

Pharmacologycontent : 14 hoursPsychotropic drugs

• Anxiolytics
• Hypnotics
• Neuroleptics
• Mood Regulators
• Antidepressants

Medications used in neurology

• Anti-epileptics

Pain and Inflammation

• Peripheral analgesics
• NSAIDs, glucocorticoids
• Medications used for asthma and COPD

Pharmacokinetics: 10 hours– lecture + 6 hours – tutorial I-Pharmacokinetics ADME stages: each stage will be described

• The journey through the body
• The mechanisms involved (tissue and cellular passages, biotransformations, etc.)
• Factors limiting the movement of the active ingredient
• Characteristic pharmacokinetic parameters

I-a. Absorption phase (oral route only) I-b. Distribution phase I-c. Metabolism phase I-d. Excretion phase II- Pharmacokinetic analysis: II-a. Calculation of pharmacokinetic parameters by non-compartmental analysis II-b. Calculation of pharmacokinetic parameters by compartmental analysis:

• Concept of pharmacokinetic modeling
• Analysis after IV administration: 1-compartment model
• Analysis after IV administration: 2-compartment model
• Analysis after oral administration: 1-compartment model

Toxicology: 6p.m.

• Describe the general principle of the metabolization stage of an AP contained in a pharmaceutical product after administration to humans:

– Describe the different stages of PA functionalization and conjugation – Describe the mechanisms behind variations in metabolism (age, pathology, enzyme induction and inhibition phenomena, etc.)

• Describe the different modes of action of a toxic substance (action on DNA, lipids, proteins depending on the different characteristics of a toxin), detoxification systems.
• Ethanol toxicology: general information, fate in the body (ADME), mechanisms of toxic action, symptoms
• Paracetamol toxicology: fate in the body, mechanisms of toxic action, symptoms
• Main stages of clinical investigation: preclinical studies (acute toxicity studies, subacute toxicity studies, mutagenicity studies, teratogenicity studies, local tolerance studies)

– 5 ECTS – Objectives Through therapeutic chemistry courses, students must acquire solid knowledge of the families of drugs covered. The therapeutic chemistry course describes the classification of each family of drugs, addressing structure, structure-activity relationships, physicochemical properties related to pharmacokinetic parameters, and therapeutic indications related to pharmacokinetics. The objectives of the "peptide synthesis" section are:

• to understand the uses of peptides in the field of health (as active ingredients and pharmacological tools) as well as the main techniques used to produce peptide collections.
• to propose a synthesis strategy and know how to implement it in a practical way, in order to obtain a simple peptide.
• to know how to analyze a peptide and purify it by chromatography.

Content Therapeutic chemistry 30 hours

• Nomenclature of drugs (INN and brand name)
• Cardiovascular system medications (beta blockers, ACE inhibitors, sartans, diuretics, antianginal drugs, lipid-lowering drugs)
• Medications used in neurology (anti-Parkinson's, anti-Alzheimer's)
• Pain and inflammation (anti-asthmatics, NSAIDs, glucocorticoids, anti-ulcer drugs, analgesics, antihistamines)
• Medications used in infectious disease treatment (ß-lactams and antiretrovirals)
• Cancer drugs
• Biotechnology-derived drugs (immunosuppressants, insulins, etc.)

Peptide synthesis (12 hours of lectures and 8 hours of practical work)

• Peptides: general information and uses in healthcare
• Principle of synthesis on a medium, concepts of automation
• The different strategies for peptide synthesis, protective groups, activating agents
• Solid-phase peptide synthesis (Fmoc/tBu strategy)
• Synthesis of peptide collections: Practical work involving split/mix synthesis of a bank of 8 tripeptides, LC/MS analysis.

– 5 ECTS – Objectives  Acquire basic knowledge of biomaterials:

• Knowledge of the main classes of biomaterials, their properties, and their main applications: polymers, metals, and ceramics.
• Understanding the various prerequisites for biomaterials for use in implantable medical devices or tissue engineering matrices
• Understanding the biomaterial/cell interactions that govern tissue integration of biomaterials
• Learn about the different 3D printing modes and the methodology for 3D printing: from computer-aided design to g-code editing and printing.
•  Know the main methods of polymer synthesis
• Know the macromolecular parameters characteristic of a polymer
• Knowing the techniques used to characterize polymers
• Understanding the link between properties and applications, particularly biomedical applications

TU  contentTU Lectures (30 hours) Biomaterials:

•  General information on biomaterials: Metals, ceramics, and bioglasses
• Introduction to biomaterial/cell interactions for implantable materials
• Polymers:
• General knowledge: History of polymers and major industrial applications; Macromolecular properties versus degradation
• Synthesis: Main methods of polymer synthesis and their impact on properties
• Macromolecular parameters and characterization: Molecular weights; Crystallinity; Glass transition
• Introduction to Natural Polymers in Health
• Innovative Forming Techniques: Introduction to 3D Printing Techniques

– 3 ECTS – Objectives: Understand how the pharmaceutical industry works and what it does, and gain an overview of the different careers available to students. Students will be able to:

• Describe the different stages of drug development.
• Describe the missions of the main regulatory agencies (ANSM, EMA, FDA) and their organization/functioning.
• Find a text in the main regulatory repositories (CSP, Eudralex, 21 CFR, ICH, etc.)
• Describe the principles of Good Clinical Practice and Good Manufacturing Practice
• Understanding the principles of audits and inspections
• Explain the clinical trial process, the people involved, and their roles.
• Describe the contents of the CTD and explain how and what Module 3 consists of.

Contents:

• I- General information about the pharmaceutical industry. Drug life cycle
• II- Regulatory institutions for medicines around the world (France, Europe, USA, WHO) and main reference standards (CSP, Eudralex, 21CFR, ICH)
• III- Good Practices in... (GMP, GCP, concept of audits and inspections)
• IV- Clinical trials: conduct, authorizations, monitoring, and management of investigational drugs
• V- Common Technical Document: Focus on Module 3

– 3ECTS – Objectives Communication: Know how to express yourself and use communication techniques in a relevant and appropriate manner PEC: Finalize the creation of your Experience and Skills Portfolio Content Communication:

• Organize and structure your thoughts;
• Developing communication skills: narration, explanation, and argumentation;
• Boost your nonverbal communication;
• Adapt your attitudes and behaviors.

PEC

• Showcase your experience and skills
• Develop your career plan and end-of-year internship plan
• Positioning yourself when responding to a job offer
• Interviewing a professional

– English – Spanish / German / other language – 2 ECTS

ENGLISH

Objectives

• Strengthening English communication skills
• Speaking and oral interactions
• Reading and listening comprehension
• Written expression

Content

• Oral presentations
• Work on written documents and videos
• Editorial work
• Learn general English and English tailored to the professional environment

GERMAN

Objectives

• Knowledge and practice of the current language, both spoken and written
• Independent speaking
• Introduction to Specialized Language in the Medical Field
• Introduction to current events in German-speaking countries

Content

• Analysis of newspaper articles, television programs, or other authentic documents to understand various aspects of current events in Germany.
• Study of certain medical or broader scientific topics

SPANISH

Objectives

• Review the grammatical basics of Spanish and eliminate persistent gaps and differences in levels. Adapt the teaching of basic knowledge to the needs of each student.
• Understanding audio-visual materials
• Reading comprehension and translation into French
• Acquisition of specialized vocabulary
• Mastery of the Prezi presentation tool (after giving the Prezi tutorial)
• Cultural approach and work on image by the painters of the Prado
• Knowledge of various Spanish and Latin American companies
• Improving oral skills

Contents THE TEACHER GIVES:

• Scientific news article (source: El País – El Mundo)
• Video documents (Internet source)

THE STUDENT PRESENTS:

• Creation of Prezi
• Exercises and grammar lessons on a dedicated platform

– 3.5 ECTS – Objectives:

• Know how to identify the appropriate statistical methodology based on the question and the nature of the data (choice of test, conditions of application, etc.).
• Know how to implement the chosen methodology using a free tool
• Knowing how to interpret statistical results in terms of practical application
• Take a critical look at an existing methodology.

Course content: 22 hours of lectures, 16 hours of tutorials, and 10 hours of independent study

• Reminder: parametric tests (comparison of means, variances)
• Nonparametric tests
• One-way analysis of variance
• Two-way ANOVA
• Simple regression analysis
• Calculating the number of subjects
• Principal Component Analysis
• Hierarchical Classification

– 5 ECTS – Objectives: The aim is to introduce students to the process of galenic pharmacy, which involves transforming an active molecule into a high-quality, safe, and effective medicine in a form suitable for therapeutic use. Students will learn about the main pharmaceutical raw materials used in the formulation of medicines, as well as packaging materials. The main galenic forms will be presented, along with the criteria that determine their selection, formulation, manufacture, and packaging.

• General information concerning the criteria for choosing the dosage form
• Raw materials used in the formulation of drugs
• Packaging materials
• Galenic forms, their physical and chemical properties and methods of administration, the excipients used in their formulation, their packaging, and their controls.

• Lectures: 34 hours
• Tutorials: 4 hours (2 sessions of 2 hours)
• Practical work: 12 hours (4 sessions of 3 hours)

– 5 ECTS – Objectives:

• Prioritizing structural protein families
• Understand the theoretical and analytical arguments of normal and tumor cell signaling
• Know the main tools of genetic engineering

Content

• Structure/function and signaling pathways of membrane proteins, nuclear receptors, and adhesion molecules
• Fundamentals of Structural Biochemistry
• Fundamentals of genetic engineering
• Basics of oncogenesis
• Study methods: identification, measurement of expression levels, protein purification; analysis of protein complex interactions

• Lectures and tutorials MANDATORY
• 2 MANDATORY hands-on workshops throughout the day

– 5 ECTS – Objectives Gain an overview of the various careers available to graduates of the Environmental Health Project Management program.

• Health, Safety, and Environment Manager
• Quality Manager
• Product stewardship (responsible for the safety and environmental impact of products)
• Risk Assessment Expert (Health, Environment)
• Sustainable development
• Safety officer
• Etc.

Contents COURSES 

• Healthy environment: practical applications in business
• Hygiene and chemical and biological risks – the story of growing awareness
• The principles of risk assessment
• Sustainable development

EXPERIENCE FEEDBACK

• Product stewardship, SDS
• Corporate safety management by an HSE manager
• Work of the Regional Association for the Improvement of Working Conditions

– 3 ECTS – Objectives:

• Highlighting physical phenomena present at interfaces: air/liquid, liquid/liquid, and liquid/solid
• Characterization of these phenomena and understanding of the challenges involved in formulating dispersed systems in various industries: pharmaceuticals, cosmetics, agri-food, plant protection, etc. For three systems: emulsions, suspensions, and foams.
• Awareness of raw materials used in the formulation of cosmetic and pharmaceutical products.

Content LECTURES: 10 hours

• Surfactants – Dispersed systems – Liquid interfaces – Solid interfaces
• Emulsions – Foams – Suspensions

PRACTICAL WORK: 6 sessions of 3 hours each

• S. 1: Study of the phase behavior of surfactants using the ternary diagram method
• S. 2: Physicochemical characterization of surfactant mixture preparations and determination of CMC
• S. 3: Creation of a final formulation based on a phase diagram – Dermocosmetic emulsion
• S. 4: Study of the foaming and wetting power of surfactants
• S. 5: Formulation of suspensions: application to toothpastes
• S. 6: Oral presentation of students' experimental results

– 2.5 ECTS – Objectives

• Marketing: Introduction to health marketing and strategic issues in the healthcare industry
• Quality management: understanding the essential principles of quality management and learning about management tools and measurement systems
• Statistical control: Mastering the main statistical tools used in quality control for production control and for the validation of analytical control methods

Content MARKETING: 9 a.m.

• The marketing approach
• The pharmaceutical market: characteristics and analysis
• The strategic challenges facing healthcare manufacturers
• Sustainable development

THE ESSENTIAL PRINCIPLES OF QUALITY MANAGEMENT: 2 hours

• Definitions and related vocabulary
• The challenges and benefits
• Standards, certification, and accreditation

THE PROCESS APPROACH: 3 hours

• Process representation
• Process management

IMPROVEMENT : 3 hours

• The principles of continuous improvement
• Internal and external auditing

Tutorial 1: The process approach: process description, analysis, and management – 1.5 hours Tutorial 2: Continuous improvement: planning and measurement system – 1.5 hours STATISTICAL CONTROL:

• Introduction to Statistical Process Control
• Introduction to Statistical Validation in Analytical Control

– 2 ECTS – English / Spanish / German / other language

ENGLISH

Objectives

• Strengthening English communication skills
• Speaking and oral interactions
• Reading and listening comprehension
• Written expression

Content

• Oral presentations
• Work on written documents and videos
• Editorial work
• Learn general English and English tailored to the professional environment

GERMAN

Objectives

• Knowledge and practice of the current language, both spoken and written
• Independent speaking
• Introduction to Specialized Language in the Medical Field
• Introduction to current events in German-speaking countries

Content

• Analysis of newspaper articles, television programs, or other authentic documents to understand various aspects of current events in Germany.
• Study of certain medical or broader scientific topics

SPANISH

Objectives

• Review the grammatical basics of Spanish and eliminate persistent gaps and differences in levels. Adapt the teaching of basic knowledge to the needs of each student.
• Understanding audio-visual materials
• Reading comprehension and translation into French
• Acquisition of specialized vocabulary
• Mastery of the Prezi presentation tool (after giving the Prezi tutorial)
• Cultural approach and work on image by the painters of the Prado
• Knowledge of various Spanish and Latin American companies
• Improving oral skills

Contents THE TEACHER GIVES:

• Scientific news article (source: El País – El Mundo)
• Video documents (Internet source)

THE STUDENT PRESENTS:

• Creation of Prezi
• Exercises and grammar lessons on a dedicated platform

– 2 ECTS – Objectives:

• Expose students to their future profession in the industry
• Knowledge of the industrial environment, context, work processes, constraints, and document drafting

Content The two-month internship is full-time and continuous, and takes place in a private or public sector company or research laboratory. This internship can be done in France or abroad.